科研项目:
1. 相分离与内体蛋白分选,北京市自然科学基金(杰青),2021.12-2024.12,结题,参与;
2. 子 叶 发 育 与 营 养 累 积 的 机 制 , 科 技 部 973 国 家 重 大 研 究 计 划 ,2014.01-2018.08,结题,参与;
代表性成果:
1.(共同通讯) Yansong Miao*,Yanning Wang*, Xiaofeng Fang* (2025). A multidimensional view of biomolecular condensates in plant biology. Annual Review of Plant Biology. (accepted)
2.(共一第一)Wang Y#, Li S#, Marcel M#, Alexander IM, Liang Z, Zeng Y, et al. Biomolecular condensates mediate bending and scission of endosome membranes. Nature. 2024;634(8036):1204-1210. (Nature杂志同期以Research Briefing的形式对该工作进行了题为Cell membranes shaped and cut by phase-separated liquid protein condensates的报道)
3.(共一) Song L#,Wang Y#, Guo Z, Lam SM, Shui G, Cheng Y. NCP2/RHD4/SAC7, SAC6 and SAC8 phosphoinositide phosphatases are required for PtdIns4P and PtdIns(4,5)P2 homeostasis and Arabidopsis development. New Phytologist. 2021;231(2):713-25.
4.(共一) Liu J#,Wang Y#, Cheng Y. The ESCRT‐I components VPS28A and VPS28B are essential for auxin‐mediated plant development. The Plant Journal. 2020;104(6):1617-34.
5.(共一) Geng P#,Wang Y #, Fang X. 相分离与RNA的相互调控. 中国科学: 生命科学. 2024;54(4):694-705.
6.Dragwidge JM,Wang Y, Brocard L, De Meyer A, Hudeček R, Eeckhout D, et al. Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants. Nature Cell Biology. 2024;26(3):438-49.
7.Jang G, Alex LPD, Robert M, Wu Z, Liu F, Sergio GL,Wang Y, Fang X, Mark CL,Caroline D. In vivo properties of Arabidopsis FCA condensates involved in RNA 3' processing. The EMBO Journal (EMBOJ-2024-118276R; https://doi.org/10.1038/s44318-025-00394-4)
8.Geng P, Li C, Quan X, Peng J, Yao Z, Wang YH,Wang YN, et al. A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis. Cell Research 2024;35:483-96.
9.Zhang L, Thapa Magar MS,Wang Y, Cheng Y. Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis. Plant Molecular Biology. 2022;110(1-2):1-12.